Nanocatalysts have undergone explosive growth over the last few decades both in homogeneous and heterogeneous forms. During the same time, Biocatalysts -underpinning some of the oldest chemical transformations known to humans- have expanded significantly their application scope, impacting chemical synthesis in multiple industries including pharmaceuticals, fine chemicals, renewable energy production and food. Attending at continuous demand for the development of novel catalysts with high-efficiency and a broad reaction scope, we focus our research activity in optimizing the fusion between the Bio and Nano catalytic worlds by applying novel multidisciplinary strategies to finally yield multifunctional hybrid (enzymes+metal oxide NPs) nanocatalysts for advanced cascade reactions.

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Viñambres, M.; et al. Modulation of the catalytic properties of lipase B from candida antarctica by immobilization on tailor-made magnetic iron oxide nanoparticles: The key role of nanocarrier surface engineering. Polymers 2018, 10(6).

Filice, M.;* et al. Preparation of an immobilized lipase-palladium artificial metalloenzyme as catalyst in the heck reaction: Role of the solid phase. Advanced Synthesis and Catalysis, 2015357(12), 2687-2696.

Filice, M.;* et al. Synthesis of a heterogeneous artificial metallolipase with chimeric catalytic activity. Chemical Communications, 201551(45), 9324-9327.

Filice, M.;* et al. Synthesis of heterogeneous enzyme-metal nanoparticle biohybrids in aqueous media and their applications in C-C bond formation and tandem catalysisChemical Communications, 201349(61), 6876-6878.